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Description
Health Benefits
- Acts as a natural shield against viruses
- Targets the underlying causes of premature aging
- Combats age-related disease
- Boosts cellular production
- Enhances the body's overall functions, health, and vitality
- Improves Skin Hydration
- Evens Skin Tone
- Boosts Skin Elasticity
- Fight The Effects Of Aging
- Experience Mental Clarity
- Feel More Energized
Reduce wrinkles: 15 ingredients that help rejuvenate the skin, reduce wrinkles, and fight aging, suitable for all ages (20 and above). This will make you wrinkle-free, with more elastic and healthy skin, while also preventing skin aging and keeping you youthful at all times.
Boost your immune system: Our Wlesor formula also boosts your immune system, giving you a healthier state, while enhancing cognitive function and memory, and improving joint health.
Science Backed: Our PQQ,Spermidine,Ergothioneine are crafted based on scientific research. We have partnered with expert physicians to help review our products & research. We strive to educate & help you with informed decisions regarding your health.
Customers become younger and healthier after using it.💗
Frequently Asked Questions (FAQ)
How long does it take to see results?
A: Initial effects can be seen after consistently taking it for 7 days, and the longer you take it, the better the results.
Recommended age?
A: Generally recommended for individuals aged 18 and above, especially for those 30+ & 40+ who want to maintain a youthful & beautiful appearance.
What is PQQ?
A: PQQ (Pyrroloquinoline Quinone)
Pyrroloquinoline quinone (PQQ) is a potent compound with significant biological functions, primarily focused on supporting mitochondrial growth and development and providing strong antioxidant properties. These functions make PQQ highly beneficial for brain health, cardiovascular health, and metabolic function. Since the human body cannot synthesize PQQ, it must be supplemented through dietary intake.
PQQ enhances immune and nervous system functions. It participates in intracellular redox processes, promotes energy metabolism, reduces oxidative damage, and stimulates the proliferation and connectivity of neurons, aiding in memory improvement and neural function recovery. Additionally, PQQ can alleviate stress, shorten recovery times, and stimulate the release of growth factors. It also promotes angiogenesis and exhibits anti-aging effects. Research indicates that PQQ supports mitochondrial health, thereby slowing the aging process.
Since its discovery in 1979, PQQ has garnered substantial attention in nutrition and pharmacology. From 2012 onwards, it has received certifications from Health Canada (HC), the U.S. Food and Drug Administration (FDA) GRAS status, the Ministry of Health, Labour and Welfare of Japan (MHLW), and the European Food Safety Authority (EFSA).
What is spermidine?
A: Spermidine, also known as triamine hydrochloride, is a polyamine widely distributed in living organisms. It is known for inhibiting neuronal nitric oxide synthase (nNOS), binding and precipitating DNA, purifying DNA-binding proteins, and stimulating T4 polynucleotide kinase activity. Notably, spermidine is recognized for its ability to delay aging and extend lifespan.
Key Longevity Benefits of Spermidine:
1. Promoting Autophagy for Longevity Autophagy is a process where cells degrade and recycle their aging and damaged parts to repair or generate new cells. This self-maintenance system allows cells to eliminate dysfunctional components, preventing accelerated aging and serious diseases like cancer and metabolic disorders. Increased gene expression of autophagy reduces cell death and extends lifespan.
Supporting Research:
- 2016 Nobel Prize in Physiology or Medicine: Awarded to molecular cell biologist Yoshinori Ohsumi for discoveries on autophagy mechanisms.
- 2009 Cell Biology Study: Published in Nature Cell Biology, showing that spermidine significantly upregulates autophagy-related genes, enhancing autophagy, inhibiting oxidative stress, and extending the lifespan of yeast, nematodes, and fruit flies.
- 2012 British Journal of Pharmacology: Demonstrated that natural polyamines spermidine and spermine prevent osteoporosis in postmenopausal mice.
- 2014 Scientific Reports: Showed that improving gut microbiota increases spermidine and spermine levels in the blood, preventing aging in mice.
- 2015 Cell Metabolism: Found that polyamine levels regulate circadian rhythms in cultured cells and mice, with spermidine supplementation reversing age-related circadian rhythm disturbances.
- Rejuvenation Research: A cross-sectional study in central Italy revealed that older adults had lower levels of spermidine and spermine, but centenarians maintained high levels comparable to younger individuals.
- 1984 Mechanisms of Ageing and Development: Documented that polyamine levels, including spermidine, decline with age in animals and humans.
Spermidine and Brain Health:
2. Benefits for Brain and Cognitive Function Natural spermidine can prevent age-related memory decline and common neurodegenerative diseases such as Alzheimer's and Parkinson's. German and Austrian researchers published their findings in Nature Neuroscience, showing that spermidine restores cognitive function in aged fruit flies, which share molecular memory processes with humans.
Supporting Research:
- Professor Stephan Sigrist and Professor Frank Madeo: Demonstrated that spermidine feeding improves brain performance and memory in aging fruit flies.
- 2009 Nature Cell Biology: Madeo's earlier work showing spermidine-induced autophagy promoting longevity.
- Future Human Applications: Researchers aim to test spermidine's effects on human memory and neurodegenerative diseases, anticipating significant breakthroughs in delaying dementia onset.
Additional Benefits of Spermidine:
3. Delaying Protein Aging Spermidine affects different molecular weight proteins, preventing the degradation of critical high molecular weight proteins that control aging processes. By enhancing the synthesis or preventing the degradation of these proteins, spermidine delays aging.
4. Rejuvenating Ovarian Function A 2023 study published in Nature Aging by Nanjing Agricultural University showed that spermidine supplementation rejuvenates oocyte quality and delays ovarian aging in mice.
5. Optimizing Cardiovascular Health Spermidine promotes autophagy and protects heart function. Studies have shown that higher blood spermidine levels correlate with better survival rates in acute myocardial infarction patients, suggesting its potential as a predictive biomarker and therapeutic supplement.
6. Anti-Inflammatory Properties Spermidine has been shown to alleviate inflammatory responses in conditions like rheumatoid arthritis and inflammatory bowel disease by blocking pathways such as NF-κB and MAPKs.
7. Neuroprotection and Regeneration Spermidine promotes nerve regeneration and protects against neurodegenerative diseases. It has been shown to enhance retinal ganglion cell survival and optic nerve regeneration, improve memory in aged fruit flies, and mitigate Parkinson's disease-related neurodegeneration.
8. Potential Anti-Cancer Effects Spermidine supplementation has been linked to reduced tumor incidence in mice and improved anti-tumor immune responses, suggesting its potential in cancer prevention and treatment.